3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzodiazepine
Izithethantonye:3-(10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE; I-AMTRIPTYLINEHYDROCHLORIDE98+%; I-AMTRIPTYLINEHYDROCHLORIDESOLUTION; 3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE
Inombolo yeCAS:59469-33-9
Ifomula yemolekyuli: C20H24ClN
Ubunzima beMolekyuli:313.86
Inombolo ye-EINECS:208-964-6
Ulwakhiwo
Isicelo:Amachiza, abaphakathi, i-APIs, i-custom synthesis, iikhemikhali
Ukongama:Umthengisi ogqwesileyo, uMgangatho oPhezulu, iXabiso loKhuphiswano, ukuhanjiswa ngokukhawuleza, ukuPhendula ngokukhawuleza
Usebenzisa:I-Antidepressant, esebenzayo kwiimpawu ezahlukeneyo zokudakumba kunye ne-organic psychosis
Iindidi ezinxulumeneyo:I-BiogenicAmineTransportInhibitors; Uphando lweBiogenicAmineTransportInhibitorsObesity; usasazo lwemithambo-luvo; I-Neurotransmission(Ukutyeba); iiNeurotransmitters; iAdrenoceptor; iiamines; IziPhakathi&zamachiza; Amachiza
Indawo yokunyibilika | 196-197°C |
Indawo yokuflasha | 11 °C |
Ukuxinana | 1.3134 (uqikelelo olurhabaxa) |
Isalathiso sokuqhafaza | 1.5490(uqikelelo) |
Ukunyibilika | H2O; enyibilikayo |
Ifom | umgubo |
pKa | 9.4(nge25℃) |
PH | 4.5~6.0 (10g/l, 25℃) |
Umbala | mhlophe ukuya kumhlophe |
Ukunyibilika kwamanzi | Phantse elubala |
Ikhowudi yeCandelo leHazard | 23/24/25-36/37/38-42/43-63-39/23/24/25-11-50/53-36-22 |
Iingxelo zoKhuseleko | 22-26-36/37/39-45-36/37-16-61-60-7 |
Uthutho lwempahla eyingozi No | UN 2811 6.1/PG 3 |
WGK eJamani | 3 |
RTECS | HO9450000 |
Inqanaba lengozi | 6.1(b) |
Udidi lokupakisha | III |
Ikhowudi ye-HS | 29214990 |
Iinkcukacha ezikhethekileyo ngokweemfuno zabathengi | |
Imbonakalo | Ikristale emhlophe okanye emhlophe, phantse umgubo omhlophe |
Ilahleko ekomisweni | 0.5% ubuninzi |
Indawo yokunyibilika | 195-199℃ |
Intsalela ekutshisweni | 0.1%ubuninzi |
Ubunyulu (HPLC) | 98.0%-102.0% (kwisiseko sokomisa) |
ImiGangatho yoMgangatho | Ushicilelo lwe-USP36 |
Imiqathango yokuphatha ngokukhuselekileyo:
Ukuphatha kwindawo engena umoya. Nxiba iimpahla ezifanelekileyo zokuzikhusela. Kuphephe ukudibana nolusu namehlo. Kuphephe ukubunjwa kothuli kunye ne-aerosols. Sebenzisa izixhobo ezingatshisiyo. Thintela umlilo obangelwa ngumphunga wokukhupha i-electrostatic.
Imiqathango yogcino olukhuselekileyo, kuquka nakuphi na ukungahambelani:
Gcina isikhongozeli sivalwe ngokuqinileyo kwindawo eyomileyo nengena umoya. Ubushushu bokugcina obucetyiswayo: 2 - 8 deg C. Gcina kwindawo eyomileyo. Amitriptyline hydrochloride.
I-Jingye ineesethi ze-86 ze-reactors iyonke, apho ivolomu ye-enamel reactor yi-69, ukusuka kwi-50 ukuya kwi-3000L. Inani le-reactors ezingenasici li-18, ukusuka kwi-50 ukuya kwi-3000L. I-QC ixhotyiswe ngamakhulu azo zonke iintlobo zezixhobo zokuhlalutya. Iyakwazi ukuhlangabezana nemveliso yorhwebo kunye nohlalutyo olubanzi lwemveliso. Le mveliso yimveliso yendawo ephezulu kwaye inokuhanjiswa ngokweemfuno zabathengi.
Ulawulo lweJingye loShishino kunye nemisebenzi yemveliso ithobela ngokungqongqo iimfuno ze-GMP, ezinceda iJingye Pharmaceutical ukuthumela iimveliso zayo eYurophu, eMelika naseMzantsi naseMpuma Asia. Ngendawo yokuvelisa yala maxesha, izixhobo zokuhlalutya eziphambili kunye nenkqubo ye-EHS evakalayo, i-Jingye Pharmaceutical iye yaqinisekiswa yi-ISO9001, ISO14001 kunye ne-GB/T28001, kwaye ngoku ikwinkqubo yoMvelisi oqeqeshiweyo we-GMP Pharmaceuticals.