I-Moxonidine kunye ne-Moxonidine HCL (Inombolo ye-CAS: 75438-57-2)
Izithethantonye:4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMIN;4-CHLORO-6-METHOXY-2-METHYL-5-(2 -IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL;
Inombolo yeCAS:75438-57-2
Ifomula yemolekyuli:C9H12ClN5O
Ubunzima beMolekyuli:241.68
Inombolo ye-EINECS:629-833-3
Isicelo:Amachiza, abaphakathi, i-APIs, i-custom synthesis, iikhemikhali
Ulwakhiwo
Ukongama:Umthengisi ogqwesileyo, uMgangatho oPhezulu, iXabiso loKhuphiswano, ukuhanjiswa ngokukhawuleza, ukuPhendula ngokukhawuleza
Usebenzisa:Iziyobisi ezichasene ne-antihypertensive azinayo imiphumo ecacileyo kwinkqubo ye-nervous central
Iindidi ezinxulumeneyo:API's; Ivumba elimnandi; IiHeterocycles; IziPhakathi kunye naMachiza aLungileyo; Amachiza; API; Cardiovascular APIs
| Indawo yokunyibilika | 217-219 ° (dec) |
| Indawo yokubilisa | 364.7±52.0 °C(Kuxelwe kwangaphambili) |
| Ukuxinana | 1.52±0.1 g/cm3(Kuxelwe kwangaphambili) |
| Ukunyibilika | Kancinci kakhulu ukunyibilika emanzini, ukunyibilika kancinci kwi-methanol, ukunyibilika kancinane kwi-methylene chloride, kancinane kakhulu ukunyibilika kwi-acetonitrile. |
| Ifom | Icocekile |
| pKa | 7.11±0.10(Kuqikelelwe) |
| Ukunyibilika kwamanzi | 800.3mg/L(iqondo lobushushu alichazwanga) |
| Uthutho lwempahla eyingozi No | UN 2811 6.1/PG III |
| WGK eJamani | 3 |
| RTECS | UV6260290 |
| Inqanaba lengozi | 6.1 |
| Udidi lokupakisha | III |
| Iinkcukacha ezikhethekileyo ngokweemfuno zabathengi | |
| Imbonakalo | Mhlophe ukuya phantse kumhlophe okuqinileyo |
| Ilahleko ekomisweni | 1.0% ubuninzi |
| Izinto ezinxulumeneyo | 1.0% ubuninzi |
| Intsalela ekutshisweni | 0.1% ubukhulu |
| Ubunyulu | 98.0％min |
Imiqathango yokuphatha ngokukhuselekileyo:
Ukuphatha kwindawo engena umoya. Nxiba iimpahla ezifanelekileyo zokuzikhusela. Kuphephe ukudibana nolusu namehlo. Kuphephe ukubunjwa kothuli kunye ne-aerosols. Sebenzisa izixhobo ezingatshisiyo. Thintela umlilo obangelwa ngumphunga wokukhupha i-electrostatic.
Imiqathango yogcino olukhuselekileyo, kuquka nakuphi na ukungahambelani:
Gcina isikhongozeli sivalwe ngokuqinileyo kwindawo eyomileyo, epholileyo nengena umoya. Gcina ngaphandle kwizikhongozeli zokutya okanye izinto ezingahambelaniyo.
R&D Iqela
Isakhiwo esizimeleyo se-R&D esakhiweni esilingwayo esizimeleyo Iqela loPhando lobuNgcali (iinkosi ezi-4 kunye neenjineli ezi-5 eziphezulu, abanye baphumelele) Izixhobo zovavanyo lobuchwephesha uJingye usebenza ngokubambisana neBeijing zhongguancun yepaki yesayensi yobomi, iShanghai Organic Chemical Research Institute of Chinese Academy of Sciences, IYunivesithi yaseNanjing , iYunivesithi yaseTshayina yezamayeza. UJingye ukwasebenzisana namashishini aphesheya kweelwandle.
Iqela le-QC
Yiba nesakhiwo sobugcisa se-QC iisethi ze-7 ze-HPLC, ngokulandelanayo: I-Agilent LC1260, i-Shimadzu LC2030 njl. Iisethi ze-6 ze-GC (Shimadzu njl.)Isethi enye ye-Infrared spectrometer (Shimadzu), Isethi enye ye-UV Spectrometer, iiseti ze-6 ze-Biochemical mold incubator njl. Iseti enye yebhokisi yovavanyo lozinzo lweDrug (ubomi obungunaphakade), Iseti enye yebhokisi yovavanyo olubanzi lokuzinza kweziyobisi (ubomi obungunaphakade) iiseti ezi-2 zeziyobisi ezipholileyo ze-2-8℃ (Haier), Iseti enye yebhokisi yogcino lobushushu obuphantsi ( Haier) njl.