I-Moxonidine kunye ne-Moxonidine HCL (Inombolo ye-CAS: 75438-57-2)
Izithethantonye:4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMIN;4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)IDINECRIM;
Inombolo yeCAS:75438-57-2
Ifomula yeemolekyuli:C9H12ClN5O
Ubunzima beMolekyuli:241.68
Inombolo ye-EINECS:629-833-3
Isicelo:Amachiza, abaphakathi, i-APIs, i-custom synthesis, iikhemikhali
Ulwakhiwo
Ukongama:Umthengisi ogqwesileyo, uMgangatho oPhezulu, iXabiso loKhuphiswano, ukuhanjiswa ngokukhawuleza, ukuPhendula ngokukhawuleza
Usebenzisa:Iziyobisi ezichasene ne-antihypertensive azinayo imiphumo ecacileyo kwinkqubo ye-nervous central
Iindidi ezinxulumeneyo:API's; Ivumba elimnandi; IiHeterocycles; IziPhakathi kunye naMachiza aLungileyo; Amachiza; API; Cardiovascular APIs
| Indawo yokunyibilika | 217-219 ° (dec) |
| Indawo yokubilisa | 364.7±52.0 °C(Kuxelwe kwangaphambili) |
| Ukuxinana | 1.52±0.1 g/cm3(Kuxelwe kwangaphambili) |
| Ukunyibilika | Kancinci kakhulu ukunyibilika emanzini, ukunyibilika kancinci kwi-methanol, ukunyibilika kancinane kwi-methylene chloride, kancinane kakhulu ukunyibilika kwi-acetonitrile. |
| Ifom | Icocekile |
| pKa | 7.11±0.10(Kuqikelelwe) |
| Ukunyibilika kwamanzi | 800.3mg/L(iqondo lobushushu alichazwanga) |
| Uthutho lwempahla eyingozi No | UN 2811 6.1/PG III |
| WGK eJamani | 3 |
| RTECS | UV6260290 |
| Inqanaba lengozi | 6.1 |
| Udidi lokupakisha | III |
| Iinkcukacha ezikhethekileyo ngokweemfuno zabathengi | |
| Imbonakalo | Mhlophe ukuya phantse kumhlophe okuqinileyo |
| Ilahleko ekomisweni | 1.0% ubuninzi |
| Izinto ezinxulumeneyo | 1.0% ubuninzi |
| Intsalela ekutshisweni | 0.1% ubukhulu |
| Ubunyulu | 98.0％min |
Imiqathango yokuphatha ngokukhuselekileyo:
Ukuphatha kwindawo engena umoya. Nxiba iimpahla ezifanelekileyo zokuzikhusela. Kuphephe ukudibana nolusu namehlo. Kuphephe ukubunjwa kothuli kunye ne-aerosols. Sebenzisa izixhobo ezingatshisiyo. Thintela umlilo obangelwa ngumphunga wokukhupha i-electrostatic.
Imiqathango yogcino olukhuselekileyo, kuquka nakuphi na ukungahambelani:
Gcina isikhongozeli sivalwe ngokuqinileyo kwindawo eyomileyo, epholileyo nengena umoya. Gcina ngaphandle kwizikhongozeli zokutya okanye izinto ezingahambelaniyo.
R&D Iqela
Isakhiwo esizimeleyo se-R&D esilingwayo esizimeleyo Iqela loPhando lobuNgcali (iinkosi ezi-4 kunye neenjineli ezi-5 eziphezulu, abanye baphumelele) Izixhobo zovavanyo lobuchwephesha uJingye usebenza ngokubambisana neBeijing zhongguancun yepaki yesayensi yobomi, iShanghai Organic Chemical Research Institute of Chinese Academy of Sciences, University Nanjing, Chinese Pharmaceutical University. UJingye ukwasebenzisana namashishini aphesheya kweelwandle.
Iqela le-QC
Yiba nesakhiwo sobugcisa se-QC iisethi ze-7 ze-HPLC, ngokulandelanayo: I-Agilent LC1260, i-Shimadzu LC2030 njl. Iisethi ze-6 ze-GC (Shimadzu njl.)Isethi enye ye-Infrared spectrometer (Shimadzu), Isethi enye ye-UV Spectrometer, iiseti ze-6 ze-Biochemical mold incubator, Isethi enye ye-Incubator ye-Drug stability (I-experimenti eyodwa ye-Drug stability life etc. ibhokisi yokulinga uzinzo lwechiza (ubomi obungunaphakade ) iiseti ezi-2 zamachiza oNyango apholileyo we-2-8℃ (Haier), Iseti enye yebhokisi yogcino lobushushu obuphantsi (Haier) njl.