I-Dibenzonoberone kwishishini lamayeza

I-Dibenzonoberone, indawo yekhemikhali yemichiza ekhulayo kuPhando lwamayeza, ivele njengenxalenye ebalulekileyo kuphuhliso lweNodeli. Eli nqaku lihlala libaluleke ukubaluleka kwayo, izicelo, kunye nezinto ezinokubakho kwiyeza lokuqhubela phambili. Ngokuqonda iipropathi zayo kunye nokusetyenziswa kwayo, iingcali zamachiza zinokusebenzisa amandla ayo ukulungisa iingxaki zokucinezelwa kwezempilo.

Ukuqonda i-DIBENZOZUROFONO

I-Dibenzonoberone kukuphazamiseka kwe-sublerone, ibonakaliswe yi-bicyclical yebhayisikile eyenza kwipropathi eyongeziweyo yekhemikhali. Inkqubo yayo eyahlukileyo yemolekyuli ivumela ukuba inxibelelane neethagethi ezahlukeneyo zebhayiloji, ezenza isithako esiphambili kuphando ezininzi kunye nophuhliso lwamachiza. Njengoko uphando lwamayeza luyaqhubeka luvela, ukuhlolwa kweekhompawundi ezinje nge-Dibenzonoberone kubalulekile ekutyhileni iindlela ezintsha zonyango.

Izicelo zoPhuculo lweziyobisi

1. Unyango lwe-anticialr:

I-Dibenzonoberone ifundwa kakhulu ngenxa ye-oncology. Amandla ayo okwenza indlela yeselula ibaluleke kakhulu kumhlaza wokuqhubela phambili kwenza umgqatswa othembisayo ekuqulunqweni konyango. Abaphandi bafumanise ukuba iipropathi zayo zibonakalisa iipropathi zeCytotoge, ezinokwenziwa ukuba zithintele ukukhula kwamathumba ngelixa kuncipha ukwenzakala kwiiseli ezisempilweni.

I-2. Iiarhente ze-neuroproprocectiveive:

Iimpawu zolwakhiwo zolwakhiwo ziye zavela inzala kwi-neuroscience. I-Dibenzonoberone kunye ne-analog yayo iphantsi kophando ngendima yazo kwi-neuronteration, kunye nezicelo ezinokubakho ekunyangeni izifo ze-neurodegenege kunye ne-alzheimer's kunye neParkinson's. Ngokunyanzela uxinzelelo lwe-oxidative kunye nokuvuvukala, ezi ziqokelelo zinokuthi zinikele ukukhululeka kwizigulana eziphethwe ziimeko ze-neuroting.

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Ukuvuvukala okungapheliyo lungunobangela wezifo ezahlukeneyo, kubandakanya isifo samathambo kunye nokuphazamiseka kwentliziyo. Iipropathi zikaDibenzonoberone ze-Dibenzosuberone ze-Demolmatory ziyaziphononongwa ukuphuhlisa unyango olunokunciphisa ngokufanelekileyo ukuvuvukala ngaphandle kweziphumo ebezinxulumene neziyobisi.

Izibonelelo ze-wibenzonoberone kuphando

Ukuzinza kwemichiza: Ulwakhiwo lwemichiza

Ukusebenza ngokutshintsha kwemali: Isakhelo sayo semolekyuli sivumela ukulungiswa, ukuvumela abaphandi ukuba balungelelanise iipropathi zayo kwiimfuno ezithile zonyango.

• I-biomatisi-uphononongo lophando lubonisa ukuba i-DIBenzonoberone ibonisa ukwenziwa kwe-biomiting ephezulu, ebaluleke kakhulu ekuqinisekiseni ukhuseleko lwezigulana kwizicelo zeklinikhi.

Imiceli mngeni kunye namathuba

Ngelixa i-Dibenzonoberone ibonisa isithembiso esikhulu, imiceli mngeni isasalela ukwamkelwa komntwana abengowakho. I-synthesis ye-wibenzonoberone kunye neziganeko zayo zinokuba nzima kwaye zinobuchule. Nangona kunjalo, ukuqhubela phambili ngeendlela zokhetho kuvula indlela yeenkqubo ezifanelekileyo zemveliso.

Ngaphaya koko, ukusebenzisana phakathi kwabafundi kunye nomzi-mveliso wamayeza kubalulekile ukuvula amandla apheleleyo e-dibenzonoberone. Ngokuphathwa gadalala kunye nobuchule, abathathi-nxaxheba banokukhawulezisa ukukhula kweziyobisi ezithetha ngeemfuno zonyango.

Ukukhuthaza incoko kunye nokusebenzisana

Ikamva le-Dibenzosuberone kwishishini lamayeza lilele kwincoko evulekileyo kunye neenzame zentsebenziswano. Iinkampani kunye nabaphandi bayakhuthazeka ukuba babelane nabanye ngezinto abazifumeneyo kunye nokuqonda ukukhawulezisa inkqubela phambili. Ukuthatha inxaxheba kwiiNkomfa zeShishini, ukupapasha uphando, kunye nokwenza umanyano lobuchule ziindlela ezifanelekileyo zokukhulisa izinto ezintsha.

Ukuqukumbela

I-Dibenzonoberone imele umkhuseli othembisayo kwiSayensi yeShememusogical. Ukusetyenziswa kwayo gwenxa, ukusebenza kwawo, kunye nezicelo ezinokubakho kwiindawo ezahlukeneyo zonyango ezigxininisa ukubaluleka kwayo kunyango lwanamhlanje. Njengoko uphando luyaqhubeka nokutyhila amandla ayo, i-DIBenzonoberone inokwenza indlela yokunyanga okuziindlela zokuphucula iziphumo zoguli kunye nokomeleza umgangatho wobomi.

Ngeengcali kwishishini lamayeza, uhambo kunye ne-wibenzonoberone sisiqalo nje. Ngokuhlala usebenza kwaye waziqonda, ungaphambili kolu phuhliso, inegalelo kwinkqubela phambili exhasa izicelo kwihlabathi liphela.

Ukufumana ezinye zeengcebiso kunye neengcali zengcali, nceda uqhagamshelaneJiangSU Jingye Pharmaceutical Co., Ltd.Ngolwazi lwamva nje kwaye siya kukubonelela ngeempendulo ezineenkcukacha.