Ithini i-pharmacogical?

Kwi-pharmacology, eziphakathi ziingqungquthela ezenziwe ukusuka kwizithintelo ezilula, zihlala zisetyenziswa kwimveliso elandelayo yeemveliso ezinzima, ezinje ngethafa elisebenzayo (APIS).

I-Expept ibalulekile kwiNkqubo yokuPhuhliswa kweZiyophu kunye neMveliso ngenxa yokuba ziququzelela ukuphendula kweekhemikhali, ukunciphisa iindleko, okanye ukwandisa isivuno seziyobisi. Abantu abaphakathi banokuba nefuthe lonyango okanye banokuba yityhefu kwaye ke bengafanelekanga ukuba basebenzise abantu.

I-InterpEDIS zenziwa ngexesha lokutyibilika kwezinto ezingafunekiyo kwaye zizinto ezinemiphumo yonyango kwiziyobisi. I-APIS ngamacandelo aphambili amayeza kwaye amisele umgangatho, ukhuseleko kunye nokusebenza kwamayeza. I-APIS iqhele ukudityaniswa kwezinto ezingafunekiyo okanye imithombo yendalo kwaye iphinde iqengqele kwaye ivunywe ngaphambi kokuba isetyenziselwe ukusetyenziswa ngabantu.

Umahluko ophambili phakathi kwe-EPEP kunye ne-APIS kukuba amaxabiso aphakathi anegalelo kwimveliso ye-APIS, ngelixa i-APIs zinegalelo ngokuthe ngqo kwimiphumo yonyango. Izakhiwo nemisebenzi yamaziko aphakathi alula kwaye ayichazwanga, ngelixa izinto zeziyobisi zinezinto ezintsonkothileyo kunye nemisebenzi. I-Expreed ineemfuno eziphantsi zomthetho kunye nokuqinisekiswa komgangatho, ngelixa i-APIS ixhomekeke kwimigangatho engqongqo engqongqo kunye nolawulo lomgangatho.

Izikhundla eziphakathi zisetyenziswa ngokubanzi kwiinkalo ezahlukeneyo kunye namashishini anje ngeekhemikhali ezihle, ze-bitechnology, kunye neekhemikhali zezolimo. I-Interpemed ikwaphuhliswa kwaye ikhula ngokuvela kweentlobo ezintsha kunye neendlela ezintsha eziphakathi, ezinjenge chiral eziphakathi, eziphakathi eziphakathi, i-Pept.

I-ExpeepS yi-backbone ye-sumemacologlogy yanamhlanje njengoko ivumela ukuba i-synthesis kunye nemveliso ye-APIs kunye namayeza. Izithintelo ziphambili ekwenzeni ukulungelelaniswa, ukulungelelaniswa komgangatho kwi-pharmacology, ukubonelela ngomgangatho ongcono weziyobisi kunye nokusebenza.